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FMN1 antibody (AA 651-750)

FMN1 Reactivity: Human, Rat WB, ELISA, IF (p), IF (cc), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1714537
  • Target See all FMN1 Antibodies
    FMN1 (Formin 1 (FMN1))
    Binding Specificity
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 651-750
    Reactivity
    • 25
    • 15
    • 2
    Human, Rat
    Host
    • 23
    • 3
    Rabbit
    Clonality
    • 25
    • 1
    Polyclonal
    Conjugate
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FMN1 antibody is un-conjugated
    Application
    • 22
    • 12
    • 12
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Dog,Cow,Sheep
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human FMN1/Formin 1
    Isotype
    IgG
    Top Product
    Discover our top product FMN1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    FMN1 (Formin 1 (FMN1))
    Alternative Name
    FMN1/Formin 1 (FMN1 Products)
    Synonyms
    si:dkey-81b15.10 antibody, fmn antibody, formin antibody, FMN antibody, LD antibody, BB164513 antibody, Fmn antibody, formin-1 antibody, ld antibody, RGD1306349 antibody, RGD1310100 antibody, formin 1 antibody, fmn1 antibody, FMN1 antibody, Fmn1 antibody
    Background

    Synonyms: FMN, Formin 1, Formin1, Formin-1, LD, Limb deformity protein homolog, FMN1_HUMAN.

    Background: The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively.

    Gene ID
    342184
    Pathways
    Regulation of Actin Filament Polymerization
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