ACAA1 antibody (AA 231-330)

Catalog No. ABIN1714588

This Rabbit Polyclonal antibody specifically detects ACAA1 in WB, ELISA, IF (cc), IF (p), ICC, IHC (p) and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for ACAA1 antibody (AA 231-330) (ABIN1714588)

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACAA1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ACAA1 Antibody

Binding Specificity: AA 231-330

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ABLIM3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for ACAA1

Target: ACAA1 (Acetyl-CoA Acyltransferase 1 (ACAA1))

Alternative Name: ACAA1

Background:

Synonyms: 3 ketoacyl CoA thiolase peroxisomal, 3-ketoacyl-CoA thiolase, ACAA, ACAA1, Acetyl CoA acyltransferase 1, Acetyl Coenzyme A acyltransferase 1, Acetyl-CoA acyltransferase, Acetyl-Coenzyme A acyltransferase 1 peroxisomal 3 oxoacyl Coenzyme A, Beta ketothiolase, Beta-ketothiolase, Peroxisomal 3 oxoacyl CoA thiolase, Peroxisomal 3 oxoacyl Coenzyme A thiolase, Peroxisomal 3-oxoacyl-CoA thiolase, peroxisomal, PTHIO, THIK_HUMAN, THIO.

Background: ACAA1 is a 424 amino acid member of the thiolase family of enzymes and is involved in lipid metabolism. Localized to the peroxisome, ACAA1 catalyzes the conversion of acyl-CoA and acetyl-CoA to 3-oxoacyl-CoA in the fatty acid oxidation pathway. ACAA1 shows high enzymatic activity in liver, kidney, intestine and white adipose tissue in rats, where it exists as two types, namely type A and type B. Human ACAA1 shares 86 % amino acid identity with its rat counterpart, suggesting a conserved function for ACAA1 among different species.

Gene ID: 30

Pathways: Monocarboxylic Acid Catabolic Process