FUBP3 antibody (AA 21-120)

Catalog No. ABIN1714775

Product Details anti-FUBP3 Antibody

Target: FUBP3 (Far Upstream Element (FUSE) Binding Protein 3 (FUBP3))

Binding Specificity: AA 21-120

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUBP3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FUBP3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FUBP3

Target: FUBP3 (Far Upstream Element (FUSE) Binding Protein 3 (FUBP3))

Alternative Name: FUBP3 (FUBP3 Products)

Synonyms: FBP3 antibody, Marta2 antibody, A330051M14Rik antibody, AV006371 antibody, zgc:101598 antibody, far upstream element binding protein 3 antibody, far upstream element-binding protein 3 antibody, far upstream element binding protein 3 S homeolog antibody, far upstream element (FUSE) binding protein 3 antibody, FUBP3 antibody, LOC100196681 antibody, Fubp3 antibody, fubp3.S antibody, fubp3 antibody

Background:

Synonyms: Far upstream element FUSE binding protein 3, Far upstream element binding protein 3, Far upstream element-binding protein 3, FBP3, FLJ25229, FUBP 3, FUBP3, FUBP3_HUMAN, FUSE binding protein 3, FUSE-binding protein 3, OTTHUMP00000022369.

Background: Activation of FUSE, the far-upstream element, is required for the proper ex-pression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein or Far upstream element binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxyl-terminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation.

Gene ID: 8939