FUBP3 antibody (AA 21-120)

Catalog No. ABIN1714775

The Rabbit Polyclonal anti-FUBP3 antibody is suitable to detect FUBP3 in samples from Human. It has been validated for WB, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for FUBP3 antibody (AA 21-120) (ABIN1714775)

Target: FUBP3 (Far Upstream Element (FUSE) Binding Protein 3 (FUBP3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FUBP3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-FUBP3 Antibody

Binding Specificity: AA 21-120

Purpose: FUBP3 Polyclonal Antibody

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FUBP3

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for FUBP3

Target: FUBP3 (Far Upstream Element (FUSE) Binding Protein 3 (FUBP3))

Alternative Name: FUBP3

Background:

Synonyms: Far upstream element FUSE binding protein 3, Far upstream element binding protein 3, Far upstream element-binding protein 3, FBP3, FLJ25229, FUBP 3, FUBP3, FUBP3_HUMAN, FUSE binding protein 3, FUSE-binding protein 3, OTTHUMP00000022369.

Background: Activation of FUSE, the far-upstream element, is required for the proper ex-pression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP (FUSE-binding protein or Far upstream element binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL60 cells, FBP, FBP2, and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxyl-terminal activation domains. Expression of FBP is detected in undifferentiated cells and is substantially decreased following cellular differentiation.

Gene ID: 8939