AGPAT5 antibody (AA 188-285)

Catalog No. ABIN1714843

This Rabbit Polyclonal antibody specifically detects AGPAT5 in ELISA, IF (cc), IF (p), IHC (p), IHC (fro) and ICC. It exhibits reactivity toward Human and Ratand has been mentioned in 1 publication.

Quick Overview for AGPAT5 antibody (AA 188-285) (ABIN1714843)

Target: AGPAT5 (1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (Lysophosphatidic Acid Acyltransferase, Epsilon) (AGPAT5))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AGPAT5 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-AGPAT5 Antibody

Binding Specificity: AA 188-285

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Cow,Sheep,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LPAAT-epsilon/AGPAT5

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-AGPAT5 antibody (ABIN1714843)

Angenendt, Reuter, Kentrup, Benk, Neumann, Hüve, Martens, Schwöppe, Kessler, Schmidt, Sauer, Brand, Mikesch, Lenz, Mesters, Müller-Tidow, Hartmann, Wardelmann, Neri, Berdel, Roesli, Schliemann: "An atlas of bloodstream-accessible bone marrow proteins for site-directed therapy of acute myeloid leukemia." in: Leukemia, Vol. 32, Issue 2, pp. 510-519, (2017) (PubMed).

Target Details for AGPAT5

Target: AGPAT5 (1-Acylglycerol-3-Phosphate O-Acyltransferase 5 (Lysophosphatidic Acid Acyltransferase, Epsilon) (AGPAT5))

Alternative Name: LPAAT-epsilon/AGPAT5

Background:

Synonyms: 1 acyl sn glycerol 3 phosphate acyltransferase epsilon, 1 acylglycerol 3 phosphate O acyltransferase 5, 1 AGP acyltransferase 5, 1 AGPAT 5, 1 AGPAT5, 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon, 1-acylglycerol-3-phosphate O-acyltransferase 5 lysophosphatidic acid acyltransferase, epsilon, 1-acylglycerol-3-phosphate O-acyltransferase 5, 1-AGP acyltransferase 5, 1-AGPAT 5, 1acylglycerol3phosphate Oacyltransferase 5 lysophosphatidic acid acyltransferase, epsilon, 1acylglycerol3phosphate Oacyltransferase 5, 1acylglycerol3phosphate Oacyltransferase5 lysophosphatidic acid acyltransferase, epsilon, 1AGP acyltransferase 5, 1AGPAT5, AGPAT5, LPAAT e, LPAAT epsilon, LPAAT-epsilon, LPAATE, Lysophosphatidic acid acyltransferase epsilon, PLCE_HUMAN.

Background: Phosphatidic acid and lysophosphatidic acid are phospholipids involved in lipid biosynthesis and signal transduction. LPAAT-epsilon (lysophosphatidic acid acyltransferase epsilon, also designated 1-AGP acyltransferase 5 (AGPAT5)) catalyzes the synthesis of phosphatidic acid from lysophosphatidic acid. LPAAT-epsilon is a membrane-bound protein belonging to the LPAAT family. Members of the LPAAT family have a well-known role in lipid biosynthesis and they may also play a role in tumor progression. LPAAT-epsilon is expressed in a tissue-specific manner in prostate and testis. LPAAT-epsilon is most closely related to AGPAT8, which is highly expressed in heart.

Gene ID: 55326