DAPK2 antibody (pSer318)

Catalog No. ABIN1714924

This Rabbit Polyclonal antibody specifically detects DAPK2 in WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) and ICC. It exhibits reactivity toward Human.

Quick Overview for DAPK2 antibody (pSer318) (ABIN1714924)

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAPK2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Product Details anti-DAPK2 Antibody

Binding Specificity: pSer318

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human DAP Kinase 2 around the phosphorylation site of Ser318

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for DAPK2

Target: DAPK2 (Death-Associated Protein Kinase 2 (DAPK2))

Alternative Name: DAP Kinase 2

Background:

Synonyms: DAP Kinase 2 phospho S318, p-DAP Kinase 2 phospho S318, Death associated protein kinase 2, DAK 2, DAK2, DAP kinase related protein 1, DAPK 2, DAPK2, Death associated protein kinase 2, DRP 1, DRP1, DRP-1, MGC119312, DAP kinase 2, DAP kinase related protein 1, DAP kinase related protein 1 beta isoform, DAP-kinase-related protein 1, DAPK 2, DAPK2, DAPK2_HUMAN, Death associated protein kinase 2, Death-associated protein kinase 2, DRP 1, DRP-1, DRP1, MGC119312.

Background: Protein kinase termed (DAPK2) dependant on calcium/calmodulin (Ca2+/CaM) contains an N-terminal protein kinase domain followed by a conserved CaM-binding domain with significant homologies to those of DAP kinase, a protein kinase involved in apoptosis. Overexpression of DAPK2 significantly induced the morphological changes characteristic of apoptosis. Results indicate that DAPK2 is an additional member of DAP kinase family involved in apoptotic signaling.

Gene ID: 23604