IBA57 antibody (AA 131-230)

Catalog No. ABIN1714942

This Rabbit Polyclonal antibody specifically detects IBA57 in WB, IF (cc), IF (p), IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for IBA57 antibody (AA 131-230) (ABIN1714942)

Target: IBA57 (IBA57, Iron-Sulfur Cluster Assembly Homolog (IBA57))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IBA57 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-IBA57 Antibody

Binding Specificity: AA 131-230

Purpose: C1orf69 Polyclonal Antibody

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C1orf69

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IBA57

Target: IBA57 (IBA57, Iron-Sulfur Cluster Assembly Homolog (IBA57))

Alternative Name: C1orf69

Background:

Synonyms: C1orf69, CA069_HUMAN, CAF17_HUMAN, FLJ12734, FLJ13849, IBA57, IBA57 iron sulfur cluster assembly homolog, IBA57 iron sulfur cluster assembly homolog S. cerevisiae, Iron sulfur cluster assembly factor for biotin synthase and aconitase like, Iron-sulfur cluster assembly factor homolog, mitochondrial, Mitochondrial proteins with a mass of 57 kDa, Putative transferase C1orf69, Putative transferase C1orf69 mitochondrial, Putative transferase CAF17, mitochondrial.

Background: Belonging to the CAF17 subfamily of the gcvT family, C1orf69 is a 356 amino acid mitochondrial protein that is required for normal heme synthesis. Heme synthesis is dependent upon receiving iron through iron sulfur (Fe-S) cluster biogenesis proteins such as C1orf69, which is specifically thought to assemble Fe-S clusters for mitochondrial aconitase and lipoate synthase. In zebrafish, deficiency of C1orf69 causes anemia. The gene encoding C1orf69 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1.

Gene ID: 200205