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C1ORF53 antibody (AA 81-145)

C1ORF53 Reactivity: Rat ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1714972
  • Target See all C1ORF53 products
    C1ORF53 (Chromosome 1 Open Reading Frame 53 (C1ORF53))
    Binding Specificity
    • 14
    • 5
    • 4
    AA 81-145
    Reactivity
    • 14
    • 9
    Rat
    Host
    • 23
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C1ORF53 antibody is un-conjugated
    Application
    ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Cow,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf51
    Isotype
    IgG
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Morgenstern, Peikert, Lübbert, Suppanz, Klemm, Alka, Steiert, Naumenko, Schendzielorz, Melchionda, Mühlhäuser, Knapp, Busch, Stiller, Dannenmaier, Lindau, Licheva, Eickhorst, Galbusera, Zerbes, Ryan et al.: "Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. ..." in: Cell metabolism, Vol. 33, Issue 12, pp. 2464-2483.e18, (2022) (PubMed).

  • Target
    C1ORF53 (Chromosome 1 Open Reading Frame 53 (C1ORF53))
    Alternative Name
    C1orf53 (C1ORF53 Products)
    Synonyms
    chromosome 1 open reading frame 53 antibody, C1orf53 antibody
    Background

    Synonyms: C1orf53, CA053_HUMAN, Chromosome 1 open reading frame 53, Hypothetical protein LOC388722, Uncharacterized protein C1orf53.

    Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf53 gene product has been provisionally designated C1orf53 pending further characterization.

    Gene ID
    388722
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