C9orf21 antibody (AA 101-200)

Catalog No. ABIN1714985

The Rabbit Polyclonal anti-C9orf21 antibody is suitable to detect C9orf21 in samples from Human. It has been validated for WB, IF (cc), IF (p), IHC (fro) and IHC (p).

Quick Overview for C9orf21 antibody (AA 101-200) (ABIN1714985)

Target: C9orf21 (AAED1) (AhpC/TSA Antioxidant Enzyme Domain Containing 1 (AAED1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C9orf21 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C9orf21 Antibody

Binding Specificity: AA 101-200

Purpose: C9orf21 Polyclonal Antibody

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C9orf21

Isotype: IgG

Application Details

Application Notes: WB(1:300-5000),

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C9orf21

Target: C9orf21 (AAED1) (AhpC/TSA Antioxidant Enzyme Domain Containing 1 (AAED1))

Alternative Name: C9orf21

Background:

Synonyms: C9orf21, AAED1_HUMAN, RP11-392G7.2, UPF0308 protein C9orf21.

Background: C9orf21 (chromosome 9 open reading frame 21) is a 226 amino acid protein that belongs to the UPF0308 family and is encoded by a gene that maps to human chromosome 9q22.33. Chromosome 9 consists of about 145 million bases, represents 4 % of the human genome and encodes nearly 900 genes. Thought to play a role in gender determination, deletion of the distal portion of 9p can lead to development of male to female sex reversal, the phenotype of a female with a male X,Y genotype. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, is associated with the chromosome 9 gene encoding endoglin protein, ENG. Familial dysautonomia is also associated with chromosome 9 though through the gene IKBKAP. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in the translocation leading to the aberrant production of BCR-ABL fusion protein often found in leukemias.

Gene ID: 195827