GEN1 antibody (AA 51-150)

Catalog No. ABIN1715019

The Rabbit Polyclonal anti-GEN1 antibody (ABIN1715019) specifically detects GEN1 in WB, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) and ICC. The antibody is reactive with Human samples.

Quick Overview for GEN1 antibody (AA 51-150) (ABIN1715019)

Target: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GEN1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-GEN1 Antibody

Binding Specificity: AA 51-150

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GEN1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GEN1

Target: GEN1 (Gen Endonuclease Homolog 1 (GEN1))

Alternative Name: GEN1

Background:

Synonyms: DKFZp781F0986, Flap endonuclease GEN homolog 1, FLJ40869, GEN 1, Gen, Gen homolog 1 endonuclease Drosophila, Gen homolog 1 endonuclease, GEN_HUMAN, GEN1.

Background: Endonuclease which cleaves flap structures at the junction between single-stranded DNA and double-stranded DNA. Specific for 5'-overhanging flap structures in which the 5'-upstream of the flap is completely double-stranded. Prefers the blocked-flap structures similar to those occurring at replication forks, in which the 5' single-strand overhang of the flap is double-stranded.

Pathways: DNA Damage Repair