C4BP antibody (AA 1-100)

Catalog No. ABIN1715092

This Rabbit Polyclonal antibody specifically detects C4BP in WB, IF (cc), IF (p), ICC, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Human.

Quick Overview for C4BP antibody (AA 1-100) (ABIN1715092)

Target: C4BP (C4-Binding Protein (C4BP))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C4BP antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-C4BP Antibody

Binding Specificity: AA 1-100

Cross-Reactivity: Human

Predicted Reactivity: Rat,Dog

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C4 binding protein

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C4BP

Target: C4BP (C4-Binding Protein (C4BP))

Alternative Name: C4 binding protein

Background:

Synonyms: C4b binding protein beta chain, C4b-binding protein beta chain, C4BP, C4BPB, C4BPB_HUMAN, Complement component 4 binding protein beta, Complement component 4 binding protein beta chain, Complement component 4-binding protein beta, OTTHUMP00000034288, OTTHUMP00000034289, OTTHUMP00000034375, OTTHUMP0000003474, Proline rich protein, PRP.

Background: C4BPB is a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants