Ankyrin G antibody (C-Term)
Quick Overview for Ankyrin G antibody (C-Term) (ABIN1721457)
Target
See all Ankyrin G (ANK3) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- C-Term
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Specificity
- Reacts with human, mouse and rat Ankyrin-G.
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Purification
- Purified
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Immunogen
- Fusion protein corresponding to ~1,000 C-terminal amino acids of human Ankyrin G
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Isotype
- IgG1
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Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC20 μg/mL WB1 - 2 μg/mL -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS pH 7.4, 50 % glycerol
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- Dilute in PBS or medium that is identical to that used in the assay system.
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Storage
- -20 °C
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Storage Comment
- Stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.
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Expiry Date
- 12 months
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- Ankyrin G (ANK3) (Ankyrin 3, Node of Ranvier (Ankyrin G) (ANK3))
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Alternative Name
- Ankyrin-G
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Background
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Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton. Ankyrins have binding sites for the beta subunit of spectrin and for at least 12 families of integral membrane proteins. This linkage is required to maintain the integrity of the plasma membranes and to anchor specific ion channels, ion exchangers, and ion transporters in the plasma membrane.
Ankyrin-3, ANK-3 Ankyrin-G Gene name: ANK3 ANKYRIN-G, MRT37 -
Gene ID
- 288
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UniProt
- Q12955
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Pathways
- Synaptic Membrane, Maintenance of Protein Location, Skeletal Muscle Fiber Development
Target
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