MUC16 antibody

Catalog No. ABIN1721473

This Mouse Monoclonal antibody specifically detects MUC16 in WB, ELISA, IHC (p) and FACS. It exhibits reactivity toward Human.

Quick Overview for MUC16 antibody (ABIN1721473)

Target: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This MUC16 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Clone: X75

Product Details anti-MUC16 Antibody

Specificity: Reacts with human CA-125.

Purification: Purified

Immunogen: CA-125 purified from ovarian carcinoma cells.

Isotype: IgG1

Application Details

Application Notes: Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
FC (0.1 μg for 106 cells) IHC-P (1 - 5 μg/mL) WB (1 - 5 μg/mL)

Positive control: Positive control: OVCAR3 ovarian adenocarcinoma cells.

Restrictions: For Research Use only

Handling

Buffer: 10 mM Tris buffer, pH 7.5, 0.15 M NaCl, 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Dilute in PBS or medium that is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: These antibodies are stable for at least one year at -20°C. Avoid multiple freeze-thaw cycles.

Target Details for MUC16

Target: MUC16 (CA125) (Mucin 16, Cell Surface Associated (CA125))

Alternative Name: CA-125

Background: CA-125 (cancer antigen 125, carcinoma antigen 125, or carbohydrate antigen 125) also known as mucin 16 or MUC16 is encoded by the MUC16 gene in humans.MUC16 is a member of the mucin family of glycoproteins. CA-125 is most consistently elevated in epithelial ovarian cancer, but can be expressed in a number of gynecologic (endometrial, fallopian tube) and nongynecologic (pancreatic, breast, colon and lung) cancers. It may also be elevated in cases of benign abnormalities such as endometriosis.

MUC16, mucin 16 cancer antigen 125, carcinoma antigen 125, carbohydrate antigen 125

Gene ID: 94025

UniProt: Q8WXI7