S100A1 antibody

Catalog No. ABIN1724663

There are 2+ publications for this product available. The Mouse Monoclonal anti-S100A1 antibody is suitable to detect S100A1 in samples from Human. It has been validated for IHC and ELISA.

Quick Overview for S100A1 antibody (ABIN1724663)

Target: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This S100A1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Clone: 2C8B8

Product Details anti-S100A1 Antibody

Purpose: S100A1 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of S100A1 expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-S100A1 antibody (ABIN1724663)

Koenig, Wojcieszyn, Weeks, Modiano: "Expression of S100a, vimentin, NSE, and melan A/MART-1 in seven canine melanoma cells lines and twenty-nine retrospective cases of canine melanoma." in: Veterinary pathology, Vol. 38, Issue 4, pp. 427-35, (2001) (PubMed).

Hoyaux, Decaestecker, Heizmann, Vogl, Schäfer, Salmon, Kiss, Pochet: "S100 proteins in Corpora amylacea from normal human brain." in: Brain research, Vol. 867, Issue 1-2, pp. 280-8, (2000) (PubMed).

Target Details for S100A1

Target: S100A1 (S100 Calcium Binding Protein A1 (S100A1))

Alternative Name: S100A1

Background: S100 calcium binding protein A1 (S100-alpha/ S100A1), it is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in stimulation of Ca2+-induced Ca2+ release, inhibition of microtubule assembly, and inhibition of protein kinase C-mediated phosphorylation. Reduced expression of this protein has been implicated in cardiomyopathies.

Gene ID: 6271

UniProt: P23297

Pathways: Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades, S100 Proteins