Ret Proto-Oncogene antibody (AA 896-1063)

Catalog No. ABIN1724678

The Mouse Monoclonal anti-Ret Proto-Oncogene antibody has been validated for ELISA. It is suitable to detect Ret Proto-Oncogene in samples from Human. There are 2+ publications available.

Quick Overview for Ret Proto-Oncogene antibody (AA 896-1063) (ABIN1724678)

Target: Ret Proto-Oncogene (RET)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Ret Proto-Oncogene antibody is un-conjugated

Application: ELISA

Clone: 8D10C9

Product Details anti-Ret Proto-Oncogene Antibody

Binding Specificity: AA 896-1063

Purpose: RET Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of RET (aa896-1063) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-Ret Proto-Oncogene antibody (ABIN1724678)

Young, Anderson, Anderson: "Guidance cues involved in the development of the peripheral autonomic nervous system." in: Autonomic neuroscience : basic & clinical, Vol. 112, Issue 1-2, pp. 1-14, (2004) (PubMed).

Myers, Mulligan: "The RET receptor is linked to stress response pathways." in: Cancer research, Vol. 64, Issue 13, pp. 4453-63, (2004) (PubMed).

Target Details for Ret Proto-Oncogene

Target: Ret Proto-Oncogene (RET)

Alternative Name: RET

Background: RET (ret proto-oncogene) is a member of the cadherin superfamily and a receptor tyrosine kinase, which are cell-surface molecules that transduce signals for cell growth and differentiation. It can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Ligands that bind the Ret receptor include the glial cell line-derived neurotropic factor (GDNF) and its congeners neurturin, persephin and artemin. Alterations in the corresponding Ret gene are associated with diseases including papillary thyroid carcinoma, multiple endocrine neoplasia (type 2A and 2B), familial medullary thyroid carcinoma and a congenital developmental disorder known as Hirschsprung

Gene ID: 5979

UniProt: P07949

Pathways: RTK Signaling, Dopaminergic Neurogenesis, Regulation of Cell Size, Tube Formation