TGFBR3 antibody (AA 147-328)

Catalog No. ABIN1724752

This Mouse Monoclonal antibody specifically detects TGFBR3 in WB and ELISA. It exhibits reactivity toward Human and Mouse. It has been mentioned in 2+ publications

Quick Overview for TGFBR3 antibody (AA 147-328) (ABIN1724752)

Target: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TGFBR3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Clone: 1C5H11

Product Details anti-TGFBR3 Antibody

Binding Specificity: AA 147-328

Purpose: TGFBR3 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. Coli.

Isotype: IgG2b

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-TGFBR3 antibody (ABIN1724752)

Lambert, Huang, Mythreye, Blobe: "The type III transforming growth factor-? receptor inhibits proliferation, migration, and adhesion in human myeloma cells." in: Molecular biology of the cell, Vol. 22, Issue 9, pp. 1463-72, (2011) (PubMed).

Jiang, Liu, Lei, You, Zhou, Zhang: "[Defective expression of TGFBR3 gene and its molecular mechanisms in non-small cell lung cancer cell lines]." in: Zhongguo fei ai za zhi = Chinese journal of lung cancer, Vol. 13, Issue 5, pp. 451-7, (2010) (PubMed).

Target Details for TGFBR3

Target: TGFBR3 (Transforming Growth Factor, beta Receptor III (TGFBR3))

Alternative Name: TGFBR3

Background: This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Molecular Weight: 93.4 kDa

UniProt: Q03167