TRAFD1 antibody (AA 401-582)

Catalog No. ABIN1724774

There are 2+ publications for this product available. The Mouse Monoclonal anti-TRAFD1 antibody is suitable to detect TRAFD1 in samples from Human. It has been validated for ELISA, FACS and ICC.

Quick Overview for TRAFD1 antibody (AA 401-582) (ABIN1724774)

Target: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TRAFD1 antibody is un-conjugated

Application: ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Clone: 8E6E7

Product Details anti-TRAFD1 Antibody

Binding Specificity: AA 401-582

Purpose: TRAFD1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TRAFD1 (AA: 401-582) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-TRAFD1 antibody (ABIN1724774)

Sanada, Takaesu, Mashima, Yoshida, Kobayashi, Yoshimura: "FLN29 deficiency reveals its negative regulatory role in the Toll-like receptor (TLR) and retinoic acid-inducible gene I (RIG-I)-like helicase signaling pathway." in: The Journal of biological chemistry, Vol. 283, Issue 49, pp. 33858-64, (2008) (PubMed).

Mashima, Saeki, Aki, Minoda, Takaki, Sanada, Kobayashi, Aburatani, Yamanashi, Yoshimura: "FLN29, a novel interferon- and LPS-inducible gene acting as a negative regulator of toll-like receptor signaling." in: The Journal of biological chemistry, Vol. 280, Issue 50, pp. 41289-97, (2005) (PubMed).

Target Details for TRAFD1

Target: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Alternative Name: TRAFD1

Background: The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses

Molecular Weight: 64.8 kDa

UniProt: O14545