TRAFD1 antibody (AA 1-50)

Catalog No. ABIN7450253

Product Details anti-TRAFD1 Antibody

Target: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Binding Specificity: AA 1-50

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAFD1 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Purpose: Rabbit anti-FLN29 Antibody, Affinity Purified

Purification: Affinity Purified

Immunogen: Between AA 1 and 50

Isotype: IgG

Application Details

Application Notes:

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for TRAFD1

Target: TRAFD1 (TRAF-Type Zinc Finger Domain Containing 1 (TRAFD1))

Alternative Name: FLN29 (TRAFD1 Products)

Synonyms: MGC80116 antibody, fln29 antibody, MGC89491 antibody, TRAFD1 antibody, 1110008K06Rik antibody, Fln29 antibody, FLN29 antibody, TRAF-type zinc finger domain containing 1 antibody, TRAF-type zinc finger domain containing 1 L homeolog antibody, TRAF-type zinc finger domain-containing protein 1 antibody, TRAF type zinc finger domain containing 1 antibody, TRAFD1 antibody, trafd1.L antibody, trafd1 antibody, trad1 antibody, Trafd1 antibody

Background: Background: FLN29 is a negative feedback regulator that controls excessive innate immune responses. It regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. FLN29 may inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation It may negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3 (By similarity) [taken from the Universal Protein Resource (UniProt) O14545].

Gene ID: 10906

NCBI Accession: NP_001137378

UniProt: O14545