Keratin 5 (KRT5) (AA 316-590) antibody

Details for Product No. ABIN1724835, Supplier: Log in to see
Antigen
  • 3300001P10Rik
  • AW146334
  • CK5
  • K5
  • Krt2-5
  • Tfip8
  • DDD
  • DDD1
  • EBS2
  • KRT5A
  • Sak57
  • ckii
  • wu:fb02h09
  • wu:fj02d02
  • wu:fk78b12
  • zfCKII
  • KRT75
  • CK-5
  • Keratin-5
  • keratin 5
  • Krt5
  • KRT5
  • krt5
Epitope
AA 316-590
32
20
16
16
9
6
6
5
5
5
4
2
2
2
2
2
1
1
1
1
Reactivity
Human
266
84
79
16
15
12
5
5
4
4
4
3
3
3
3
2
2
1
1
Host
Mouse
139
138
6
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
14
9
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
228
156
119
93
62
47
47
19
16
11
10
4
3
2
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen Purified recombinant fragment of human CK5 (AA 316-590) expressed in E. Coli.
Clone 2C2B4
Isotype IgG1
Purification Purified
Antigen
Alternative Name CK5 (KRT5 Antibody Abstract)
Background The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the basal layer of the epidermis with family member KRT14. Mutations in these genes have been associated with a complex of diseases termed epidermolysis bullosa simplex. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.
Molecular Weight 62.3 kDa
Gene ID 3852
HGNC 3852
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
ELISA image for anti-Keratin 5 (KRT5) (AA 316-590) antibody (ABIN1724835) anti-Keratin 5 (KRT5) (AA 316-590) antibody
Flow Cytometry (FACS) image for anti-Keratin 5 (KRT5) (AA 316-590) antibody (ABIN1724835) anti-Keratin 5 (KRT5) (AA 316-590) antibody (Image 2)
Western Blotting (WB) image for anti-Keratin 5 (KRT5) (AA 316-590) antibody (ABIN1724835) anti-Keratin 5 (KRT5) (AA 316-590) antibody (Image 3)
Western Blotting (WB) image for anti-Keratin 5 (KRT5) (AA 316-590) antibody (ABIN1724835) anti-Keratin 5 (KRT5) (AA 316-590) antibody (Image 4)
Immunohistochemistry (IHC) image for anti-Keratin 5 (KRT5) (AA 316-590) antibody (ABIN1724835) Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using CK...
Immunohistochemistry (IHC) image for anti-Keratin 5 (KRT5) (AA 316-590) antibody (ABIN1724835) Immunohistochemical analysis of paraffin-embedded stomach tissues using CK5 mouse mAb...
Product cited in: Sugiyama-Fukamatsu, Suzuki, Nakanishi, Iwatsuki: "Epidermolysis bullosa nevus arising in a patient with Dowling-Meara type epidermolysis bullosa simplex with a novel K5 mutation." in: The Journal of dermatology, Vol. 36, Issue 8, pp. 447-52, 2009 (PubMed).

Grin, OMalley, Mulligan: "Cytokeratin 5 and estrogen receptor immunohistochemistry as a useful adjunct in identifying atypical papillary lesions on breast needle core biopsy." in: The American journal of surgical pathology, Vol. 33, Issue 11, pp. 1615-23, 2009 (PubMed).