RING1 antibody (AA 79-263)

Catalog No. ABIN1724839

This Mouse Monoclonal antibody specifically detects RING1 in WB, ELISA, IHC and FACS. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for RING1 antibody (AA 79-263) (ABIN1724839)

Target: RING1 (Ring Finger Protein 1 (RING1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This RING1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 8C12F4

Product Details anti-RING1 Antibody

Binding Specificity: AA 79-263

Purpose: Ring1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human Ring1 (AA: 79-263) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-RING1 antibody (ABIN1724839)

Vidal: "Role of polycomb proteins Ring1A and Ring1B in the epigenetic regulation of gene expression." in: The International journal of developmental biology, Vol. 53, Issue 2-3, pp. 355-70, (2009) (PubMed).

Target Details for RING1

Target: RING1 (Ring Finger Protein 1 (RING1))

Alternative Name: Ring1

Background: This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4.

Molecular Weight: 42.4 kDa

UniProt: Q06587