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FLIP antibody (AA 100-251)

CFLAR Reactivity: Human ELISA, IHC Host: Mouse Monoclonal 6G11A6 unconjugated
Catalog No. ABIN1724856
  • Target See all FLIP (CFLAR) Antibodies
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Binding Specificity
    • 16
    • 15
    • 15
    • 9
    • 8
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 100-251
    Reactivity
    • 104
    • 66
    • 58
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 92
    • 15
    • 2
    Mouse
    Clonality
    • 94
    • 15
    Monoclonal
    Conjugate
    • 55
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FLIP antibody is un-conjugated
    Application
    • 98
    • 39
    • 28
    • 26
    • 20
    • 20
    • 16
    • 13
    • 11
    • 10
    • 9
    • 5
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Purpose
    CFLAR Antibody
    Purification
    Purified antibody
    Immunogen
    Purified recombinant fragment of human CFLAR (AA: 100-251) expressed in E. Coli.
    Clone
    6G11A6
    Isotype
    IgG1
    Top Product
    Discover our top product CFLAR Primary Antibody
  • Application Notes
    ELISA: 1/10000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Rao-Bindal, Rao, Yu, Kleinerman: "Expression of c-FLIP in pulmonary metastases in osteosarcoma patients and human xenografts." in: Pediatric blood & cancer, Vol. 60, Issue 4, pp. 575-9, (2013) (PubMed).

    Noh, Lee, Sung, Song, Kim, Woo, Kwon, Lee: "CHOP down-regulates cFLIP(L) expression by promoting ubiquitin/proteasome-mediated cFLIP(L) degradation." in: Journal of cellular biochemistry, Vol. 113, Issue 12, pp. 3692-700, (2012) (PubMed).

  • Target
    FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))
    Alternative Name
    CFLAR (CFLAR Products)
    Background

    Description: The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists.

    Aliases: CASH, FLIP, MRIT, CLARP, FLAME, Casper, FLAME1, c-FLIP, FLAME-1, I-FLICE, c-FLIPL, c-FLIPR, c-FLIPS, CASP8AP1

    Molecular Weight
    55.3kDa
    Gene ID
    8837
    HGNC
    8837
    UniProt
    O15519
    Pathways
    Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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