PLAGL1 antibody (Pleiomorphic Adenoma Gene-Like 1) (AA 118-222)

Details for Product anti-PLAGL1 Antibody No. ABIN1724869
Antigen
Epitope
AA 118-222
5
5
4
3
3
2
1
1
1
1
1
Reactivity
Human
58
22
20
7
6
4
4
4
3
3
2
2
1
Host
Mouse
49
9
Clonality (Clone)
Monoclonal ()
Conjugate
This PLAGL1 antibody is un-conjugated
5
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
39
22
13
7
6
3
2
1
1
1
1
Options
Immunogen Purified recombinant fragment of human PLAGL1 (AA 118-222) expressed in E. Coli.
Clone 8D8C5
Isotype IgG1
Purification Purified
Antigen
Alternative Name PLAGL1 (PLAGL1 Antibody Abstract)
Background This gene encodes a C2H2 zinc finger protein with transactivation and DNA-binding activities. It has been shown to have anti-proliferative properties, and thus thought to function as a tumor suppressor. In addition, overexpression of this gene during fetal development is believed to underlie the rare disorder, transient neonatal diabetes mellitus (TNDM). This gene is imprinted, with preferential expression of the paternal allele in many tissues, however, biallelic expression has been noted in peripheral blood leucocytes. A recent study reports that tissue-specific imprinting results from variable utilization of monoallelic and biallelic promoters. Many transcript variants differing in the 5' UTR and encoding two different isoforms, have been found for this gene. ,
Molecular Weight 50.8 kDa
Gene ID 5325
HGNC 5325
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Pleiomorphic Adenoma Gene-Like 1 (PLAGL1) (AA 118-222) antibody (ABIN1724869) Immunohistochemical analysis of paraffin-embedded ovarian cancer tissues using PLAGL1...
Product cited in: Liu, Hsieh, Liu, Chang, Lin, Wang, Huang: "Zac1, an Sp1-like protein, regulates human p21(WAF1/Cip1) gene expression in HeLa cells." in: Experimental cell research, Vol. 317, Issue 20, pp. 2925-37, 2011 (PubMed).