CDX1 antibody (AA 122-227)

Catalog No. ABIN1724875

This Mouse Monoclonal antibody specifically detects CDX1 in ELISA. It exhibits reactivity toward Human. It has been mentioned in 2+ publications

Quick Overview for CDX1 antibody (AA 122-227) (ABIN1724875)

Target: CDX1 (Caudal Type Homeobox 1 (CDX1))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDX1 antibody is un-conjugated

Application: ELISA

Clone: 1B11A9

Product Details anti-CDX1 Antibody

Binding Specificity: AA 122-227

Purpose: CDX1 Antibody

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human CDX1 (AA: 122-227) expressed in E. Coli.

Isotype: IgG2a

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-CDX1 antibody (ABIN1724875)

Rau, Rogler, Frischauf, Jung, Konturek, Dimmler, Faller, Sehnert, El-Rifai, Hartmann, Voll, Schneider-Stock: "Methylation-dependent activation of CDX1 through NF-κB: a link from inflammation to intestinal metaplasia in the human stomach." in: The American journal of pathology, Vol. 181, Issue 2, pp. 487-98, (2012) (PubMed).

Kang, Lee, Kim, Lee, Lee, Park, Kim, Jung, Song: "CDX1 and CDX2 expression in intestinal metaplasia, dysplasia and gastric cancer." in: Journal of Korean medical science, Vol. 26, Issue 5, pp. 647-53, (2011) (PubMed).

Target Details for CDX1

Target: CDX1 (Caudal Type Homeobox 1 (CDX1))

Alternative Name: CDX1

Background: This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.

Molecular Weight: 28.1 kDa

UniProt: P47902