Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 52-156) antibody

Details for Product No. ABIN1724902
Antigen
Epitope
AA 52-156
15
9
7
6
6
5
4
2
1
1
1
1
Reactivity
Human
99
56
40
2
2
2
2
2
2
2
1
1
1
Host
Mouse
93
14
8
1
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
11
4
4
3
3
3
3
3
3
2
2
2
1
1
1
1
1
Application
ELISA, Western Blotting (WB)
75
66
27
15
13
8
5
4
2
2
1
1
1
Options
Immunogen Purified recombinant fragment of human IGFBP7 (AA 52-156) expressed in E. Coli.
Clone 5A4A9
Isotype IgG1
Purification Purified
Antigen
Alternative Name IGFBP7 (IGFBP7 Antibody Abstract)
Background This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). ,
Molecular Weight 29.1 kDa
Gene ID 3490
HGNC 3490
Pathways Growth Factor Binding
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 52-156) antibody (ABIN1724902) anti-Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 52-156) antibody (Image 1)
Image no. 2 for anti-Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 52-156) antibody (ABIN1724902) anti-Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 52-156) antibody (Image 2)
Image no. 3 for anti-Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 52-156) antibody (ABIN1724902) anti-Insulin-Like Growth Factor Binding Protein 7 (IGFBP7) (AA 52-156) antibody (Image 3)
Product cited in: Evdokimova, Tognon, Benatar, Yang, Krutikov, Pollak, Sorensen, Seth: "IGFBP7 binds to the IGF-1 receptor and blocks its activation by insulin-like growth factors." in: Science signaling, Vol. 5, Issue 255, pp. ra92, 2012 (PubMed).