GABBR2 antibody (gamma-aminobutyric Acid (GABA) B Receptor, 2) (AA 319-483)

Details for Product anti-GABBR2 Antibody No. ABIN1724937
Antigen
Epitope
AA 319-483
27
22
18
17
15
9
7
7
5
4
3
3
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human
174
143
142
5
5
5
4
4
2
2
2
2
2
1
1
1
1
Host
Mouse
154
40
1
Clonality (Clone)
Monoclonal ()
Conjugate
This GABBR2 antibody is un-conjugated
11
9
7
6
6
6
6
6
6
4
4
4
4
4
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
128
65
52
47
34
30
22
6
4
4
1
1
1
Options
Immunogen Purified recombinant fragment of human GABBR2 (AA 319-483) expressed in E. Coli.
Clone 5G7F7
Isotype IgG2a
Purification Purified
Antigen
Alternative Name GABBR2 (GABBR2 Antibody Abstract)
Background The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence. , , , ,
Molecular Weight 105.8 kDa
Gene ID 9568
HGNC 9568
Pathways cAMP Metabolic Process
Application Notes ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
Restrictions For Research Use only
Format Liquid
Buffer PBS with 0.05 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C,-20 °C
Storage Comment 4°C, -20°C for long term storage
Supplier Images
Image no. 1 for anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (ABIN1724937) anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (Image 1)
Image no. 2 for anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (ABIN1724937) anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (Image 2)
Image no. 3 for anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (ABIN1724937) anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (Image 3)
Image no. 4 for anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (ABIN1724937) anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (Image 4)
Image no. 5 for anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (ABIN1724937) anti-gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2) (AA 319-483) antibody (Image 5)
Product cited in: Balasubramanian, Fam, Hall: "GABAB receptor association with the PDZ scaffold Mupp1 alters receptor stability and function." in: The Journal of biological chemistry, Vol. 282, Issue 6, pp. 4162-71, 2007 (PubMed).