Aggrecan antibody (N-Term)

Catalog No. ABIN1731433

Product Details anti-Aggrecan Antibody

Target: Aggrecan (ACAN)

Binding Specificity: N-Term

Reactivity: Human, Hamster, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aggrecan antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Reacts with Aggrecan from Human, Gorilla, Monkey, Hamster, Pig

Cross-Reactivity: Rat (Rattus)

Cross-Reactivity (Details): Predicted to cross react with Mouse, Rat, Bovine, Horse. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except NCAN (56 % ).

Purification: Antiserum

Immunogen: Synthetic 18 amino acid peptide from N-terminus of human ACAN / Aggrecan. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Hamster, Pig (100%), Mouse, Rat, Bovine, Panda, Horse (94%), Dog, Elephant (89%), Bat (83%).

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
IHC - P (7 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Long term: -70°C, Short term: +4°C

Target Details for Aggrecan

Target: Aggrecan (ACAN)

Alternative Name: ACAN / Aggrecan (ACAN Products)

Background: Crucial component of the extracellular matrix of cartilagenous tissue. Mutated form of Aggrecan is involved in skeletal dysplasia and spinal degeneration.

Gene ID: 176

Pathways: Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport