ACE2 antibody (Internal Region)
Quick Overview for ACE2 antibody (Internal Region) (ABIN1731442)
Target
See all ACE2 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- Internal Region
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Specificity
- Reacts with human ACE2 (internal part)
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Cross-Reactivity
- Mouse (Murine)
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Cross-Reactivity (Details)
- Cross reacts with mouse ACE2 protein.
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Purification
- Antigen affinity purified
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Immunogen
- Synthetic peptide from human ACE2.
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Isotype
- IgG
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Application Notes
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Working dilution: IHC - P (2.5 μg/mL), WB (0.5 - 2 μg/mL)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- PBS, Sodium azide 0.02 %
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
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- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
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Alternative Name
- ACE-2
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Background
- Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
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UniProt
- Q9BYF1
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Pathways
- ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
Target
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