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ACE2 antibody (Internal Region)

This Rabbit Polyclonal antibody specifically detects ACE2 in WB and IHC (p). It exhibits reactivity toward Human and Mouse.
Catalog No. ABIN1731442

Quick Overview for ACE2 antibody (Internal Region) (ABIN1731442)

Target

See all ACE2 Antibodies
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

Reactivity

  • 168
  • 59
  • 55
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
Human, Mouse

Host

  • 148
  • 45
  • 6
  • 1
Rabbit

Clonality

  • 127
  • 73
Polyclonal

Conjugate

  • 122
  • 17
  • 12
  • 8
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ACE2 antibody is un-conjugated

Application

  • 158
  • 87
  • 78
  • 50
  • 41
  • 36
  • 30
  • 18
  • 17
  • 14
  • 10
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

    • 19
    • 16
    • 12
    • 8
    • 8
    • 8
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    Specificity

    Reacts with human ACE2 (internal part)

    Cross-Reactivity

    Mouse (Murine)

    Cross-Reactivity (Details)

    Cross reacts with mouse ACE2 protein.

    Purification

    Antigen affinity purified

    Immunogen

    Synthetic peptide from human ACE2.

    Isotype

    IgG
  • Application Notes

    Working dilution: IHC - P (2.5 μg/mL), WB (0.5 - 2 μg/mL)

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    PBS, Sodium azide 0.02 %

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C/-20 °C

    Storage Comment

    Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.
  • Target

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    Alternative Name

    ACE-2

    Background

    Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.

    UniProt

    Q9BYF1

    Pathways

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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