Aryl Hydrocarbon Receptor antibody (C-Term)

Catalog No. ABIN1731978

This anti-Aryl Hydrocarbon Receptor antibody is a Rabbit Polyclonal antibody detecting Aryl Hydrocarbon Receptor in IHC (p). Suitable for Human.

Quick Overview for Aryl Hydrocarbon Receptor antibody (C-Term) (ABIN1731978)

Target: Aryl Hydrocarbon Receptor (AHR)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Aryl Hydrocarbon Receptor antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Aryl Hydrocarbon Receptor Antibody

Binding Specificity: C-Term

Specificity: Reacts with human Aryl Hydrocarbon Receptor

Cross-Reactivity (Details): BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TCHHL1 (56 % ).

Purification: Antigen affinity purified

Immunogen: Synthetic 16 amino acid peptide from C-terminus of human Aryl Hydrocarbon Receptor. Percent identity with other species by BLAST analysis: Human (100%), Gorilla (100%), Gibbon (94%), Monkey (88%), Bat (88%), Elephant (88%), Guinea pig (88%)

Isotype: IgG

Application Details

Application Notes:

Working dilution: IHC - P (15 - 20 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, Sodium azide 0.1 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-80 °C

Storage Comment: Long term: -70°C, Short term: +4°C

Target Details for Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Alternative Name: Aryl Hydrocarbon Receptor

Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues

UniProt: P35869

Pathways: Regulation of Cell Size