FLIP antibody (AA 2-18)

Catalog No. ABIN1734374

The Rabbit Polyclonal anti-FLIP antibody is suitable to detect FLIP in samples from Human, Mouse and Rat. It has been validated for WB and ICC.

Quick Overview for FLIP antibody (AA 2-18) (ABIN1734374)

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FLIP antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-FLIP Antibody

Binding Specificity: AA 2-18

Specificity: Reacts with the N-terminus part of human FLIP. Cross-reacts with mouse and rat protein.

Purification: Purified

Immunogen: Peptide corresponding to aa 2-18 of human FLIP (accession no. AAC51622). This sequence is identical in all FLIP splice variants

Isotype: IgG

Application Details

Application Notes: Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
ICC5 μg/mL WB2 μg/mL

Positive control: HeLa cells

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Dilute in PBS or medium which is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Expiry Date: 6 months

Target Details for FLIP

Target: FLIP (CFLAR) (CASP8 and FADD-Like Apoptosis Regulator (CFLAR))

Alternative Name: FLIP

Background: Involved in apoptotic process as an inhibitor of TNFRSF6 mediated apoptosis.

CASP8 and FADD-like apoptosis regulator Caspase homolog, CASH Caspase-eight-related protein, Casper Caspase-like apoptosis regulatory protein, CLARP Cellular FLICE-like inhibitory protein, c-FLIP FADD-like antiapoptotic molecule 1, FLAME-1 Inhibitor of FLICE, I-FLICE MACH-related inducer of toxicity, MRIT Gene name: CFLAR, CASH, CASP8AP1, CLARP, MRIT

Gene ID: 8837

UniProt: O15519

Pathways: Apoptosis, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development