GLI2 antibody (Internal Region)

Catalog No. ABIN1734718

This Rabbit Polyclonal antibody specifically detects GLI2 in WB, ELISA and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for GLI2 antibody (Internal Region) (ABIN1734718)

Target: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GLI2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GLI2 Antibody

Binding Specificity: Internal Region

Specificity: Reacts with Mouse Gli-2

Purification: Antigen affinity purified

Immunogen: Synthetic peptide from mouse GLI2.

Isotype: IgG

Application Details

Application Notes:

Working dilution: ELISA (1/15000 - 1/60000), IHC - P (5 μg/mL), WB (1/500 - 1/2000)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: K phosphate 20 mM, NaCl 150 mM, pH 7.2, Sodium azide 0.01 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: +4°C or -20°C, Avoid repeated freezing and thawing.

Target Details for GLI2

Target: GLI2 (GLI Family Zinc Finger 2 (GLI2))

Alternative Name: GLI2

Background: Acts as a transcriptional activator. May play a role during embryogenesis. Binds to the DNA sequence 5'-GAACCACCCA-3' which is part of the TRE-2S regulatory element that augments the Tax-dependent enhancer of human T-cell leukemia virus type 1. Implicated in the transduction of SHH signal.

UniProt: P10070

Pathways: Hedgehog Signaling, Dopaminergic Neurogenesis