IL1RAP antibody (AA 525-540)

Catalog No. ABIN1735875

The Rabbit Polyclonal anti-IL1RAP antibody (ABIN1735875) specifically detects IL1RAP in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for IL1RAP antibody (AA 525-540) (ABIN1735875)

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IL1RAP antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL1RAP Antibody

Binding Specificity: AA 525-540

Specificity: Reacts with human IL-1RAcP. Cross-reacts with mouse and rat protein. No cross-reactivity with other members of the IL-1 receptor family

Purification: Purified

Immunogen: Peptide corresponding to aa 525-540 of human IL-1RAcP. The sequence is identical to that of mouse and rat IL-1RAcP.

Isotype: IgG

Application Details

Application Notes: Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB1:1000 - 1:2000

Positive control: HeLa cells

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Dilute in PBS or medium which is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Expiry Date: 6 months

Target Details for IL1RAP

Target: IL1RAP (Interleukin 1 Receptor Accessory Protein (IL1RAP))

Alternative Name: IL-1RAcP

Background: Cellular responses induced by the proinflammatory cytokine IL-1 require two subunits of the IL-1 receptor, IL-1 receptor 1 (IL-1R1) and IL-1 receptor accessory protein (IL-1RacP). IL-1RacP forms a complex with IL-1R1 in response to IL-1 treatment.

Interleukin-1 receptor accessory protein, IL-1 receptor accessory protein, IL-1RAcP Interleukin-1 receptor 3, IL-1R-3, IL-1R3 Gene name: IL1RAP, C3orf13, IL1R3

Gene ID: 3556

UniProt: Q9NPH3

Pathways: NF-kappaB Signaling, Growth Factor Binding