TP53INP1 antibody (AA 1-14)

Catalog No. ABIN1737783

The Rabbit Polyclonal anti-TP53INP1 antibody (ABIN1737783) specifically detects TP53INP1 in WB. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TP53INP1 antibody (AA 1-14) (ABIN1737783)

Target: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TP53INP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TP53INP1 Antibody

Binding Specificity: AA 1-14

Specificity: Reacts with human p53DINP1. Cross-reacts with mouse and rat protein.

Purification: Purified

Immunogen: Peptide corresponding to aa 1-14 of human p53DINP1. This sequence is identical in p53DINP1 alpha and beta and differs from that of mouse p53DINP1 by one amino acid.

Isotype: IgG

Application Details

Application Notes: Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB: 1-2 μg/mL

Positive control: Human lung tissue

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.4

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Dilute in PBS or medium which is identical to that used in the assay system.

Storage: -20 °C

Storage Comment: Store in aliquots at -20°C. Antibodies are guaranteed for 6 months from date of receipt.

Expiry Date: 6 months

Target Details for TP53INP1

Target: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Alternative Name: p53DINP1

Background: Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy. Acts as a positive regulator of autophagy. In response to cellular stress or activation of autophagy, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, GABARAPL1/L2, MAP1LC3A/B/C and regulates autophagy. Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response.

Tumor protein p53-inducible nuclear protein 1 Stress-induced protein p53-dependent damage-inducible nuclear protein 1, p53DINP1 Gene name: TP53INP1, P53DINP1, SIP

Gene ID: 94241

UniProt: Q96A56