VAMP2 antibody (N-Term)

Catalog No. ABIN1742194

This Guinea Pig Polyclonal antibody specifically detects VAMP2 in WB, IHC, ICC, IP and IHC (p). It exhibits reactivity toward Human, Mouse, Rat and Hamster and has been mentioned in 3+ publications.

Quick Overview for VAMP2 antibody (N-Term) (ABIN1742194)

Target: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Reactivity: Human, Mouse, Rat, Hamster

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This VAMP2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-VAMP2 Antibody

Binding Specificity: N-Term

Purpose: anti-Synaptobrevin2 antiserum

Specificity: Specific for VAMP 2

Cross-Reactivity (Details): Reacts with: human (P63027), rat (P63045), mouse (P63044), hamster. No signal: chicken. Other species not tested yet.

Purification: antiserum

Immunogen: Synthetic peptide corresponding to residues near the amino terminus of rat Synaptobrevin2 (UniProt Id: P63045)

Application Details

Application Notes: WB:1 : 1000 up to 1 : 5000 , IP:yes ICC:1 : 1000, IHC:1 : 500, IHC-P:1 : 500,

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-VAMP2 antibody (ABIN1742194)

van Stegen, Dagar, Gottmann: "Release activity-dependent control of vesicle endocytosis by the synaptic adhesion molecule N-cadherin." in: Scientific reports, Vol. 7, pp. 40865, (2017) (PubMed).

Schaefer, Toral, Velez, Cox, Baker, Borcherding, Colgan, Bondada, Mashburn, Yu, Geddes, Tsang, Bassuk, Mahajan: "Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses." in: Investigative ophthalmology & visual science, Vol. 57, Issue 6, pp. 2509-21, (2016) (PubMed).

Kung, Gong, Adedoyin, Ng, Bhargava, Ohara, Jasmin: "Evidence for glutamate as a neuroglial transmitter within sensory ganglia." in: PLoS ONE, Vol. 8, Issue 7, pp. e68312, (2013) (PubMed).

Target Details for VAMP2

Target: VAMP2 (Vesicle-Associated Membrane Protein 2 (Synaptobrevin 2) (VAMP2))

Alternative Name: Synaptobrevin2

Background:

Synonyms: VAMP 2, p18-2, pain

Antigen Information: Synaptobrevin2 also known as Vamp2 is a major vesicle protein involved in fusion

UniProt: P63045

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport