Syntaxin 6 antibody (AA 1-235)

Catalog No. ABIN1742223

This anti-Syntaxin 6 antibody is a Rabbit Polyclonal antibody detecting Syntaxin 6 in WB, IP and ICC. Suitable for Human, Chicken, Mouse, Rat and Hamster. This Primary Antibody has been cited in 8+ publications.

Quick Overview for Syntaxin 6 antibody (AA 1-235) (ABIN1742223)

Target: Syntaxin 6 (STX6)

Reactivity: Human, Chicken, Mouse, Rat, Hamster

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Syntaxin 6 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Product Details anti-Syntaxin 6 Antibody

Binding Specificity: AA 1-235

Specificity: Specific for syntaxin 6.

Purification: antiserum

Immunogen: Recombinant human syntaxin 6 (aa 1-235).

Application Details

Application Notes: WB: 1 : 1000 up to 1 : 10000 (AP staining)
ICC: 1 : 500
IHC: not tested yet

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS

Handling Advice: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Storage: 4 °C/-20 °C

Storage Comment: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

References for anti-Syntaxin 6 antibody (ABIN1742223)

Du, Liu, Wu, Zhu, Tang: "Essential role of STX6 in esophageal squamous cell carcinoma growth and migration." in: Biochemical and biophysical research communications, (2016) (PubMed).

Pattu, Qu, Schwarz, Strauss, Weins, Bhat, Halimani, Marshall, Rettig, Hoth: "SNARE protein expression and localization in human cytotoxic T lymphocytes." in: European journal of immunology, Vol. 42, Issue 2, pp. 470-5, (2012) (PubMed).

Madan, Rastogi, Parashuraman, Mukhopadhyay: "Salmonella acquires lysosome-associated membrane protein 1 (LAMP1) on phagosomes from Golgi via SipC protein-mediated recruitment of host Syntaxin6." in: The Journal of biological chemistry, Vol. 287, Issue 8, pp. 5574-87, (2012) (PubMed).

Bogan, Rubin, Yu, Löffler, Orme, Belman, McNally, Hao, Cresswell: "Endoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocation." in: The Journal of biological chemistry, Vol. 287, Issue 28, pp. 23932-47, (2012) (PubMed).

Lazarevic, Schöne, Heine, Gundelfinger, Fejtova: "Extensive remodeling of the presynaptic cytomatrix upon homeostatic adaptation to network activity silencing." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 31, Issue 28, pp. 10189-200, (2011) (PubMed).

Pérez-Victoria, Bonifacino: "Dual roles of the mammalian GARP complex in tethering and SNARE complex assembly at the trans-golgi network." in: Molecular and cellular biology, Vol. 29, Issue 19, pp. 5251-63, (2009) (PubMed).

Takamori, Holt, Stenius, Lemke, Grønborg, Riedel, Urlaub, Schenck, Brügger, Ringler, Müller, Rammner, Gräter, Hub, De Groot, Mieskes, Moriyama, Klingauf, Grubmüller, Heuser, Wieland, Jahn: "Molecular anatomy of a trafficking organelle." in: Cell, Vol. 127, Issue 4, pp. 831-46, (2006) (PubMed).

Wang, Tai, Lu, Johannes, Hong, Tang: "Trans-Golgi network syntaxin 10 functions distinctly from syntaxins 6 and 16." in: Molecular membrane biology, Vol. 22, Issue 4, pp. 313-25, (2005) (PubMed).

Target Details for Syntaxin 6

Target: Syntaxin 6 (STX6)

Alternative Name: Syntaxin 6

Pathways: Synaptic Vesicle Exocytosis