SLC17A8 antibody (C-Term)

Catalog No. ABIN1742302

This Guinea Pig Polyclonal antibody specifically detects SLC17A8 in IHC and WB. It exhibits reactivity toward Rat and Mouse. It has been mentioned in 2+ publications

Quick Overview for SLC17A8 antibody (C-Term) (ABIN1742302)

Target: SLC17A8 (Solute Carrier Family 17 (Sodium-Dependent Inorganic Phosphate Cotransporter), Member 8 (SLC17A8))

Reactivity: Rat, Mouse

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This SLC17A8 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Grade: KO Validated

Product Details anti-SLC17A8 Antibody

Binding Specificity: C-Term

Purpose: anti-VGLUT3 antiserum

Specificity: Specific for mouse VGLUT 3.

Cross-Reactivity (Details): Reacts with: mouse (Q8BFU8), rat (Q7TSF2). Other species not tested yet.

Purification: antiserum

Immunogen: Synthetic peptide corresponding to residues near the carboxy terminus of mouse VGLUT3 (UniProt Id: Q8BFU8)

Application Details

Application Notes: WB:1 : 1000

Comment:

WB: Due to the low abundance of this protein in the brain, immunoblotting is difficult. This antibody works well in immunohistochemistry on 4 % para-formaldehyde / 0.1 % glutaraldehyde fixed tissue sections.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-SLC17A8 antibody (ABIN1742302)

Cao, Gou, Du, Fan, Liang, Yan, Lin, Jin, Du: "Glutamatergic and central cholinergic dysfunction in the CA1, CA2 and CA3 fields on spatial learning and memory in chronic cerebral ischemia-Induced vascular dementia of rats." in: Neuroscience letters, Vol. 620, pp. 169-176, (2016) (PubMed).

Heise, Schroeder, Schoen, Halbedl, Reim, Woelfle, Kreutz, Schmeisser, Boeckers: "Selective Localization of Shanks to VGLUT1-Positive Excitatory Synapses in the Mouse Hippocampus." in: Frontiers in cellular neuroscience, Vol. 10, pp. 106, (2016) (PubMed).

Target Details for SLC17A8

Target: SLC17A8 (Solute Carrier Family 17 (Sodium-Dependent Inorganic Phosphate Cotransporter), Member 8 (SLC17A8))

Alternative Name: VGLUT3

Background:

Synonyms: SLC17A8, Glutamate Transporter, vesicular Neurotransmitter transporter, VGLUT 3

Antigen Information: K.O. VGluT3 is a synaptic vesicle glutamate transporter

UniProt: Q8BFU8

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport