Arc antibody

Catalog No. ABIN1742333

The Mouse Monoclonal anti-Arc antibody has been validated for IP. It is suitable to detect Arc in samples from Rat and Mouse. There are 5+ publications available.

Quick Overview for Arc antibody (ABIN1742333)

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Reactivity: Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This Arc antibody is un-conjugated

Application: Immunoprecipitation (IP)

Clone: 48B2

Product Details anti-Arc Antibody

Purpose: Mouse anti-Arc IgG

Specificity: Specific for Arc.

Cross-Reactivity (Details): Reacts with: rat (Q63053), mouse (Q9WV31). Other species not tested yet.

Purification: purified IgG

Immunogen: Full-length recombinant mouse Arc (UniProt Id: Q9WV31) Epitop AA 1 to 214 from mouse Arc (UniProt Id: Q9WV31)

Isotype: IgG2b

Application Details

Application Notes: WB:not recommended IP:yes ICC:not tested yet IHC:not tested yet IHC-P:not tested yet ELISA:

Comment:

ELISA: Suitable as capture antibody for sandwich-ELISA as detector antibody (protocol for sandwich-ELISA).

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Azide was added before lyophilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

References for anti-Arc antibody (ABIN1742333)

Izumi, Ishimoto, Yamamoto, Mori: "Application of hairless mouse strain to bioluminescence imaging of Arc expression in mouse brain." in: BMC neuroscience, Vol. 18, Issue 1, pp. 18, (2017) (PubMed).

Gerace, Landucci, Totti, Bani, Guasti, Baronti, Moroni, Mannaioni, Pellegrini-Giampietro: "Ethanol Toxicity During Brain Development: Alterations of Excitatory Synaptic Transmission in Immature Organotypic Hippocampal Slice Cultures." in: Alcoholism, clinical and experimental research, Vol. 40, Issue 4, pp. 706-16, (2016) (PubMed).

Lee, Kang, Kim, Yoon, Kim, Moon: "Enhanced expression of immediate-early genes in mouse hippocampus after trimethyltin treatment." in: Acta histochemica, (2016) (PubMed).

Alvarez-Dieppa, Griffin, Cavalier, McIntyre: "Vagus Nerve Stimulation Enhances Extinction of Conditioned Fear in Rats and Modulates Arc Protein, CaMKII, and GluN2B-Containing NMDA Receptors in the Basolateral Amygdala." in: Neural plasticity, Vol. 2016, pp. 4273280, (2016) (PubMed).

Vasileva, Horstmann, Geumann, Gitler, Kuner: "Synapsin-dependent reserve pool of synaptic vesicles supports replenishment of the readily releasable pool under intense synaptic transmission." in: The European journal of neuroscience, Vol. 36, Issue 8, pp. 3005-20, (2012) (PubMed).

Target Details for Arc

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Alternative Name: Arc

Background:

Synonyms: Arg 3.1

Antigen Information: Arc is a cytoskeleton-associated protein involved in neuronal plasticity

UniProt: Q9WV31