Arc antibody (Middle Region)

Catalog No. ABIN2774829

The Rabbit Polyclonal anti-Arc antibody (ABIN2774829) specifically detects Arc in WB and IHC. The antibody is reactive with Human, Rat, Mouse, Guinea Pig, Cow and Goat samples.

Quick Overview for Arc antibody (Middle Region) (ABIN2774829)

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Reactivity: Human, Rat, Mouse, Guinea Pig, Cow, Goat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Arc antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Arc Antibody

Binding Specificity: Middle Region

Sequence: ELDLPQKQGE PLDQFLWRKR DLYQTLYVDA DEEEIIQYVV GTLQPKLKRF

Predicted Reactivity: Cow: 100%, Goat: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against ARC. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ARC

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 396 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for Arc

Target: Arc (Activity-Regulated Cytoskeleton-Associated Protein (Arc))

Alternative Name: ARC

Background: ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. The protein is also required for homeostatic synaptic scaling of AMPA receptors.
Alias Symbols: KIAA0278, Arg3.1
Protein Interaction Partner: UBE3A, UBC, KRT15,
Protein Size: 396

Molecular Weight: 45 kDa

Gene ID: 23237

NCBI Accession: NM_015193, NP_056008

UniProt: Q7LC44