SYNPO antibody (Center)

Catalog No. ABIN1742349

This anti-SYNPO antibody is a Guinea Pig Polyclonal antibody detecting SYNPO in WB, IHC, ICC and IHC (p). Suitable for Human, Mouse and Rat. This Primary Antibody has been cited in 2+ publications.

Quick Overview for SYNPO antibody (Center) (ABIN1742349)

Target: SYNPO (Synaptopodin (SYNPO))

Reactivity: Human, Mouse, Rat

Host: Guinea Pig

Clonality: Polyclonal

Conjugate: This SYNPO antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Grade: KO Validated

Product Details anti-SYNPO Antibody

Binding Specificity: Center

Purpose: anti-Synaptopodin antiserum

Specificity: Fragment used for immunization is present in all 3 isoforms.

Cross-Reactivity (Details): Reacts with: rat (Q9Z327), mouse (Q8CC35), human (Q8N3V7). Other species not tested yet.

Purification: antiserum

Immunogen: Recombinant protein corresponding to residues near the central region of mouse Synaptopodin. (UniProt Id: Q8CC35)

Application Details

Application Notes: WB:1 : 500 up to 1 : 1000 , IP:not tested yet ICC:1 : 500, IHC:1 : 200, IHC-P:1 : 200 up to 1 : 500, ExM:external data

Comment:

WB: Application is limited, the antibody is less sensitive than the rabbit antibody.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-SYNPO antibody (ABIN1742349)

Corradetti, Jog, Cesaroni, Madaio, Caricchio: "Estrogen Receptor α Signaling Exacerbates Immune-Mediated Nephropathies through Alteration of Metabolic Activity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 200, Issue 2, pp. 512-522, (2018) (PubMed).

Wang, Dumoulin, Renner, Triller, Specht: "The Role of Synaptopodin in Membrane Protein Diffusion in the Dendritic Spine Neck." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148310, (2016) (PubMed).

Target Details for SYNPO

Target: SYNPO (Synaptopodin (SYNPO))

Alternative Name: Synaptopodin

Background:

Synonyms: synpo, synpo-long, synpo-short, kidney, glomeruli, Synpo, Kiaa1029

Antigen Information: K.O. Synaptopodin is an actin associated protein present in renal podocytes and telencephalic dendrites

UniProt: Q8CC35