SYNPO antibody (C-Term)

Catalog No. ABIN783789

Product Details anti-SYNPO Antibody

Target: SYNPO (Synaptopodin (SYNPO))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SYNPO antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Synaptopodin / SYNPO at C-term.

Purification: Affinity chromatography purified via peptide column

Immunogen: Affinity chromatography purified via peptide column

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.02 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for SYNPO

Target: SYNPO (Synaptopodin (SYNPO))

Alternative Name: Synaptopodin / SYNPO (SYNPO Products)

Synonyms: SYNPO antibody, DKFZp459N012 antibody, 9030217H17Rik antibody, 9130229N11 antibody, 9330140I15Rik antibody, AW046661 antibody, synaptopodin antibody, formin-like protein 5 antibody, SYNPO antibody, LOC100147046 antibody, Synpo antibody

Background: SYNPO, also known as synaptopodin, is an actin-associated protein in telencephalic dendrites and renal podocytes. SYNPO is tightly associated with the dendritic spine apparatus, and mice lacking the SYNPO gene lack the apparatus. These SYNPO-null mice also demonstrate an impaired ability to express long-term potentiation as well as deficits in spatial memory tasks, indicating that SYNPO is involved in the regulation of synaptic plasticity. Recent studies suggest that SYNPO is linked to neuronal calcium stores and plays a role in the calcium store-associated ability of neurons to undergo long-term plasticity.Synonyms: KIAA1029

Gene ID: 11346

NCBI Accession: NP_001103444

UniProt: Q8N3V7