NEFL antibody (AA 1-284)

Catalog No. ABIN1742358

This anti-NEFL antibody is a Rabbit Polyclonal antibody detecting NEFL in WB, IHC, ICC, IP and IHC (p). Suitable for Human, Rat and Mouse. This Primary Antibody has been cited in 3+ publications.

Quick Overview for NEFL antibody (AA 1-284) (ABIN1742358)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-NEFL Antibody

Binding Specificity: AA 1-284

Purpose: Rabbit anti-Neurofilament L antiserum

Specificity: Specific for neurofilament L.

Cross-Reactivity (Details): Reacts with: human (P07196), rat (P19527), mouse (P08551). Other species not tested yet.

Purification: antiserum

Immunogen: with AA 200-292 missing. corresponds to AA 1 to 284 in AAH66952.1 (UniProt Id: P07196)

Application Details

Application Notes: WB:1 : 1000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 200 μLH2O, then aliquot and store at -20 °C until use.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Do not freeze!

References for anti-NEFL antibody (ABIN1742358)

Richard, Kurdakova, Baches, Bayer, Weggen, Wirths: "Gene Dosage Dependent Aggravation of the Neurological Phenotype in the 5XFAD Mouse Model of Alzheimer's Disease." in: Journal of Alzheimer's disease : JAD, Vol. 45, Issue 4, pp. 1223-36, (2015) (PubMed).

Pérez-García, Burden: "Increasing MuSK activity delays denervation and improves motor function in ALS mice." in: Cell reports, Vol. 2, Issue 3, pp. 497-502, (2012) (PubMed).

Wenker, Chamorro, Vota, Callero, Vittori, Nesse: "Differential antiapoptotic effect of erythropoietin on undifferentiated and retinoic acid-differentiated SH-SY5Y cells." in: Journal of cellular biochemistry, Vol. 110, Issue 1, pp. 151-61, (2010) (PubMed).

Target Details for NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Alternative Name: Neurofilament L

Background:

Synonyms: NFL, NF-L, NF-68, Neurofilament light polypeptide, 68 kDa neurofilament protein, Neurofilament triplet L protein, Nefl, Nf68, Nfl

Antigen Information: Neurofilaments are major neuronal intermediate filaments

UniProt: P07196