NEFL antibody (AA 1-284)

Catalog No. ABIN1742358

This anti-NEFL antibody is a Rabbit Polyclonal antibody detecting NEFL in WB, IHC, ICC and IP. Suitable for Human, Rat and Mouse. This Primary Antibody has been cited in 3+ publications.

Quick Overview for NEFL antibody (AA 1-284) (ABIN1742358)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NEFL antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Product Details anti-NEFL Antibody

Binding Specificity: AA 1-284

Specificity: Specific for neurofilament L.

Purification: antiserum

Immunogen: Recombinant Strep-Tag® fusion protein of human neurofilament L (aa 1-284).

Application Details

Application Notes: WB: 1 : 1000 (AP staining)
ICC: 1 : 500
IHC: 1 : 200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS

Handling Advice: Crude antisera are more robust than monoclonals. With anti-microbials added, they may be stored at 4 °C.
Serum does not contain active proteases, in fact, serum itself contains a powerful cocktail of protease inhibitors. Frozen storage (-20 °C),however, is preferable.

Storage: 4 °C/-20 °C

Storage Comment: Unlabeled antibodies are stable in this form without loss of quality at ambient temperatures for several weeks or even months. They can be stored at 4 °C for several years.

References for anti-NEFL antibody (ABIN1742358)

Richard, Kurdakova, Baches, Bayer, Weggen, Wirths: "Gene Dosage Dependent Aggravation of the Neurological Phenotype in the 5XFAD Mouse Model of Alzheimer's Disease." in: Journal of Alzheimer's disease : JAD, Vol. 45, Issue 4, pp. 1223-36, (2015) (PubMed).

Pérez-García, Burden: "Increasing MuSK activity delays denervation and improves motor function in ALS mice." in: Cell reports, Vol. 2, Issue 3, pp. 497-502, (2012) (PubMed).

Wenker, Chamorro, Vota, Callero, Vittori, Nesse: "Differential antiapoptotic effect of erythropoietin on undifferentiated and retinoic acid-differentiated SH-SY5Y cells." in: Journal of cellular biochemistry, Vol. 110, Issue 1, pp. 151-61, (2010) (PubMed).

Target Details for NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Alternative Name: Neurofilament L

Background: Synonyms: NF-L, NF 68