Otoferlin antibody (AA 181-196)

Catalog No. ABIN1742371

This Rabbit Polyclonal antibody specifically detects Otoferlin in . It exhibits reactivity toward Mouseand has been mentioned in 1 publication.

Quick Overview for Otoferlin antibody (AA 181-196) (ABIN1742371)

Target: Otoferlin (OTOF)

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Otoferlin antibody is un-conjugated

Application: Please inquire

Grade: KO Validated

Product Details anti-Otoferlin Antibody

Binding Specificity: AA 181-196

Purpose: Rabbit anti-Otoferlin antibody

Specificity: Specific for otoferlin.

Cross-Reactivity (Details): Reacts with: mouse (Q9ESF1). Other species not tested yet.

Purification: affinity purified

Immunogen: Synthetic peptide corresponding to AA 181 to 196 from mouse Otoferlin (UniProt Id: Q9ESF1-1)

Application Details

Application Notes: WB:not tested yet IP:not tested yet ICC:not tested yet IHC:external data

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 50 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References for anti-Otoferlin antibody (ABIN1742371)

Vogl, Cooper, Neef, Wojcik, Reim, Reisinger, Brose, Rhee, Moser, Wichmann: "Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells." in: Journal of cell science, Vol. 128, Issue 4, pp. 638-44, (2015) (PubMed).

Target Details for Otoferlin

Target: Otoferlin (OTOF)

Alternative Name: Otoferlin

Background:

Synonyms: Otof, Ear, Cochlea

Antigen Information: K.O. Otoferlin is a potential Ca2+ sensor of transmitter release in hair cells of the inner ear

UniProt: Q9ESF1

Pathways: Sensory Perception of Sound, Synaptic Vesicle Exocytosis