GalphaO 2 (AA 1-355) antibody

Catalog No. ABIN1742531

There are 3+ publications for this product available. The Mouse Monoclonal anti-GalphaO 2 antibody is suitable to detect GalphaO 2 in samples from Mouse and Rat. It has been validated for IP and WB.

Quick Overview for GalphaO 2 (AA 1-355) antibody (ABIN1742531)

Target: GalphaO 2

Reactivity: Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Application: Immunoprecipitation (IP), Western Blotting (WB)

Grade: KO Validated

Clone: 101-4

Product Details

Binding Specificity: AA 1-355

Purpose: Mouse anti-GalphaO2 IgG

Specificity: Specific for GalphaO 2

Cross-Reactivity (Details): Reacts with: rat (P59215), mouse (P18872). Other species not tested yet.

Purification: purified IgG

Immunogen: Recombinant protein corresponding to AA 1 to 355 from rat GalphaO2 (UniProt Id: P18872)

Isotype: IgG2b

Application Details

Application Notes: WB:1 : 1000 , IP:yes ICC:not recommended IHC:not recommended IHC-P:not tested yet

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Do not freeze!

References

Baron, Blex, Rohrbeck, Rachakonda, Birnbaumer, Ahnert-Hilger, Brunk: "The α-subunit of the trimeric GTPase Go2 regulates axonal growth." in: Journal of neurochemistry, Vol. 124, Issue 6, pp. 782-94, (2013) (PubMed).

Okawa, Pahlberg, Rieke, Birnbaumer, Sampath: "Coordinated control of sensitivity by two splice variants of Gα(o) in retinal ON bipolar cells." in: The Journal of general physiology, Vol. 136, Issue 4, pp. 443-54, (2010) (PubMed).

Winter, Brunk, Walther, Höltje, Jiang, Peter, Takamori, Jahn, Birnbaumer, Ahnert-Hilger: "Galphao2 regulates vesicular glutamate transporter activity by changing its chloride dependence." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 25, Issue 18, pp. 4672-80, (2005) (PubMed).

Target Details

Target: GalphaO 2

Alternative Name: GalphaO2

Background:

Synonyms: Gnao, Gnao2, Go2, Go2 alpha

Antigen Information: K.O. GalphaO1 and 2 are G-proteins involved in the regulation of vesicular neurotransmitter transporters

UniProt: P18872