toxA antibody

Catalog No. ABIN180304

This Mouse Monoclonal antibody specifically detects toxA in EIA. It exhibits reactivity toward Clostridium difficile.

Quick Overview for toxA antibody (ABIN180304)

Target: toxA (Clostridium Difficile Toxin A (toxA))

Reactivity: Clostridium difficile

Host: Mouse

Clonality: Monoclonal

Conjugate: This toxA antibody is un-conjugated

Application: Enzyme Immunoassay (EIA)

Clone: 5155

Product Details anti-toxA Antibody

Characteristics: Synonyms: toxA, tcdA

Purification: Affinity Chromatography on Protein A.

Immunogen: Clostridium difficile toxin A

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/20-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.2, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for toxA

Target: toxA (Clostridium Difficile Toxin A (toxA))

Alternative Name: Clostridium Difficile Toxin A

Background: Clostridium difficile is a gram-positive motile bacterium which is the leading cause of diarrhoea in developed countries. The incidence of disease in humans varies greatly with age, spore density, and the administration of antibiotics. Toxin A (TcdA) is a large exotoxin which is an essential virulence factor for C. difficile infection. TcdA has a molecular weight of 308kD and is a glucosyltransferase, which irreversibly inactivates the Ras family of small GTPases to disrupt many important signalling pathways.Synonyms: tcdA, toxA

UniProt: P16154