Plakophilin 2 antibody (AA 125-139)

Catalog No. ABIN1804502

The Goat Polyclonal anti-Plakophilin 2 antibody is suitable to detect Plakophilin 2 in samples from Human, Rat, Mouse, Dog, Rabbit and Hamster. It has been validated for WB, ELISA, IHC and IHC (p).

Quick Overview for Plakophilin 2 antibody (AA 125-139) (ABIN1804502)

Target: Plakophilin 2 (PKP2)

Reactivity: Human, Rat, Mouse, Dog, Rabbit, Hamster

Host: Goat

Clonality: Polyclonal

Conjugate: This Plakophilin 2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Plakophilin 2 Antibody

Binding Specificity: AA 125-139

Specificity: Human PKP2 / Plakophilin 2. This antibody is expected to recognize both reported isoforms (NP_001005242.2, NP_004563.2).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide C-RGTAQYSSQKSVEER from an internal region of human PKP2 / Plakophilin 2 (NP_001005242.2, NP_004563.2). Percent identity by BLAST analysis: Human, Gorilla, Hamster, Dog, Rabbit (100%), Marmoset, Panda, Bovine, Bat, Horse (93%), Mouse (87%), Elephant, Opossum (80%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Approved: IHC, IHC-P (3.75 μg/mL), Peptide-ELISA (1:16000), WB (0.3 - 1 μg/mL)

Usage: Peptide ELISA: antibody detection limit dilution 1:16000. Western blot: Approx 100kD band observed in Mouse and Rat Heart lysates (calculated MW of 88.1kD according to Mouse NP_080439.1 and 87.8kD according to Rat NP_001093969.1). Recommended concentration: 0.3-1 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for Plakophilin 2

Target: Plakophilin 2 (PKP2)

Alternative Name: PKP2 / Plakophilin 2

Background: Name/Gene ID: PKP2

Synonyms: PKP2, ARVD9, Plakophilin 2, Plakophilin-2

Gene ID: 5318

NCBI Accession: NP_001005242, NP_004563

UniProt: Q99959

Pathways: Cell-Cell Junction Organization, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection