C5AR1 antibody

Catalog No. ABIN181011

The Rat Monoclonal anti-C5AR1 antibody (Clone 01-10-92) (ABIN181011) specifically detects C5AR1 in FACS and IHC (fro). The antibody is reactive with Mouse samples.

Quick Overview for C5AR1 antibody (ABIN181011)

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This C5AR1 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 01-10-92

Product Details anti-C5AR1 Antibody

Cross-Reactivity (Details): Species reactivity (tested):Mouse.

Characteristics: Synonyms: C5a-R, C5aR, C5AR1, Complement Component 5a Receptor 1, C5a anaphylatoxinchemotactic receptor

Purification: Affinity Chromatography on Protein G.

Immunogen: RBL-2H3 transfected cells expressing murine C5aR. Cells from immunised Lou/c rats werefused with cells of the X63-Ag8. 653 myeloma cell line. Genename: CD88

Isotype: IgG2a

Application Details

Application Notes: Flow Cytometry: Use 10 μL of 1/50-1/100 diluted antibody to label 1x10^6 cells in 100 μL. Immunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Alternative Name: CD88 / C5R1

Background: CD88 is a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 Molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1

UniProt: P30993

Pathways: Complement System