C5AR1 antibody (PE)

Catalog No. ABIN181016

The Rat Monoclonal anti-C5AR1 antibody is suitable to detect C5AR1 in samples from Mouse. It has been validated for FACS.

Quick Overview for C5AR1 antibody (PE) (ABIN181016)

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This C5AR1 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: 20-70

Product Details anti-C5AR1 Antibody (PE)

Characteristics: Synonyms: C5a-R, C5aR, C5AR1, Complement Component 5a Receptor 1, C5a anaphylatoxinchemotactic receptor

Purification: Affinity Chromatography on Protein G.

Immunogen: RBL-2H3 transfected cells expressing murine C5aR

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry: Use 10 μL of neat-1/10 diluted antibody to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing lowaffinity Fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Reconstitution: Restore with 1 mL distilled water.

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % BSA as stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store the antibody undiluted Prior to and Following Reconstitution at 2-8 °C. DO NOT FREEZE! This product is photosensitive and should be protected from light.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for C5AR1

Target: C5AR1 (Complement Component 5a Receptor 1 (C5AR1))

Alternative Name: CD88 / C5R1

Background: CD88 is a 45kD G-protein coupled cell surface receptor, which is otherwise known as C5aR. The CD88 Molecule functions as a receptor for the complement component C5a, which is a potent proinflammatory molecule and a chemoattractant for neutrophils to sites of infection. In mouse, CD88 is expressed on granulocytes, monocytes and macrophages but not on resting or stimulated lymphocytes.Synonyms: C5AR1, C5a anaphylatoxin chemotactic receptor, C5a-R, C5aR, Complement Component 5a Receptor 1

UniProt: P30993

Pathways: Complement System