Collagen Type V antibody

Catalog No. ABIN181165

This Goat Polyclonal antibody specifically detects Collagen Type V in WB, IHC (fro), EIA and IF. It exhibits reactivity toward Human.

Quick Overview for Collagen Type V antibody (ABIN181165)

Target: Collagen Type V (COL5) (Collagen, Type V (COL5))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Collagen Type V antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro)), Enzyme Immunoassay (EIA), Immunofluorescence (IF)

Product Details anti-Collagen Type V Antibody

Specificity: This antibody reacts to Collagen V. This antibody shows less than 10 % reactivity with collagen type I, II, III, IV, and VI. It may react with collagen V from other species. Reactivity with other ECM proteins has not been tested.

Purification: Affinity chromatography

Immunogen: Human type V collagen

Application Details

Application Notes: ELISA. Immunoblotting. Immunofluorescence. Immunohistochemistry on frozen sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0.4 mg/mL

Buffer: Borate buffered saline

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Collagen Type V

Target: Collagen Type V (COL5) (Collagen, Type V (COL5))

Alternative Name: Collagen Type V

Background: Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.Synonyms: COL5A1

Gene ID: 1289

NCBI Accession: NP_000084

UniProt: P20908