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Thymic Stromal Lymphopoietin antibody

TSLP Reactivity: Human WB, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN181720
  • Target See all Thymic Stromal Lymphopoietin (TSLP) Antibodies
    Thymic Stromal Lymphopoietin (TSLP)
    Reactivity
    • 43
    • 9
    • 7
    • 2
    • 1
    • 1
    Human
    Host
    • 49
    • 4
    • 1
    Rabbit
    Clonality
    • 48
    • 5
    • 1
    Polyclonal
    Conjugate
    • 28
    • 7
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Thymic Stromal Lymphopoietin antibody is un-conjugated
    Application
    • 43
    • 17
    • 11
    • 7
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects HumanTSLP. Other species not tested.
    Purification
    Immunoaffinity Chromatography
    Immunogen
    Highly pure (> 98%) E.coli derived recombinant Human TSLP
    Top Product
    Discover our top product TSLP Primary Antibody
  • Application Notes
    ELISA: Indirect: To detect hTSLP (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with compatible secondaryreagents, it allows the detection of at least 0.2 - 0.4 ng/well of recombinant hTSLP. Sandwich: To detect hTSLP (using 100 μL/well antibody solution) a concentration of0.5 - 2.0 μg/mL of this antibody is required. In conjunction with Biotinylated Anti-HumanTSLP as a detection antibody, it allows the detection of at least 0.2 - 0.4 ng/well ofrecombinant hTSLP. Western blot: To detect hTSLP analysis this antibody can be used at a concentration of0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant hTSLP is 1.5 - 3.0 ng/lane, under either reducing or non-reducingconditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Reconstitution
    Centrifuge vial prior to opening. Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
    Buffer
    PBS, pH 7.2
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Target
    Thymic Stromal Lymphopoietin (TSLP)
    Alternative Name
    TSLP (TSLP Products)
    Synonyms
    TSLP antibody, thymic stromal lymphopoietin antibody, TSLP antibody, Tslp antibody
    Background
    Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. Despite its predicted molecular weight, TSLP often migrates at a higher molecular weight in SDS-PAGE. At least two differentially spliced isoforms of TSLP are known to exist.Synonyms: Thymic stroma-derived lymphopoietin, Thymic stromal lymphopoietin
    Gene ID
    53603
    NCBI Accession
    NP_067342
    UniProt
    Q9JIE6
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