Macrophage Scavenger Receptor 1 antibody

Catalog No. ABIN181779

This anti-Macrophage Scavenger Receptor 1 antibody is a Rat Monoclonal antibody detecting Macrophage Scavenger Receptor 1 in WB, FACS, IP, IHC (fro), Func and EIA. Suitable for Mouse.

Quick Overview for Macrophage Scavenger Receptor 1 antibody (ABIN181779)

Target: Macrophage Scavenger Receptor 1 (MSR1)

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This Macrophage Scavenger Receptor 1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func), Enzyme Immunoassay (EIA)

Clone: 2F8

Product Details anti-Macrophage Scavenger Receptor 1 Antibody

Specificity: This antibody recognises the Murine Scavenger Receptor Class A (SRA), type I and II, also known as CD204.

Purification: Affinity Chromatography on Protein G

Endotoxin Level: Low Endotoxin

Immunogen: RAW264 cell line. Remarks: Spleen cells from immunised AO rats were fused with cells of the Y3 rat myeloma cell line.

Isotype: IgG2b

Application Details

Application Notes: ELISA. Western Blot. Functional Assays. Immunoprecipitation. Immunohistochemistry on frozen sections. Flow Cytometry: 1/50 - 1/100, Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Further Comments: Endotoxin Level: less than 0.01 EU/ug

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.4 without preservatives

Preservative: Without preservative

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Target Details for Macrophage Scavenger Receptor 1

Target: Macrophage Scavenger Receptor 1 (MSR1)

Alternative Name: CD204

Background: CD204 is expressed by tissue macrophages and functions both as an endocytic receptor for lipoproteins and as an adhesion receptor for macrophages binding to ligand rich tissues e.g. atherosclerotic lesions. Clone 2F8 inhibits the uptake of acetylated low-density lipoproteins and also inhibits divalent cation independent adhesion.Synonyms: MSR1, Macrophage acetylated LDL receptor I and II, Macrophage scavenger receptor types I and II, SCARA1, Scavenger receptor class A member 1

Gene ID: 20288

NCBI Accession: NP_001106797

UniProt: P30204