NCR1 antibody

Catalog No. ABIN1819100

The Mouse Monoclonal anti-NCR1 antibody has been validated for WB, FACS and IF. It is suitable to detect NCR1 in samples from Cow.

Quick Overview for NCR1 antibody (ABIN1819100)

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Reactivity: Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This NCR1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: AKS1

Product Details anti-NCR1 Antibody

Specificity: Clone AKS1 is specific for bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1. CD335 is a type I transmembrane protein, with two extracellular C2-type immunoglobulin-like domains, which functions as an activating receptor. CD335 is expressed by human natural killer cells. The bovine homologue is expressed on bovine NK cells and no expression of CD335 has been detected on B cells, T cells, monocytes or granulocytes. Clone AKS1 is reported to activate lysis of FcgammaR-expressing cell line P815, by IL-2 activated NKp46+ cells.

Purification: Protein G purified

Immunogen: Fusion protein consisting of the extracellular region of bovine CD335.

Type of Immunogen: Fusion protein

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for NCR1

Target: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Alternative Name: NCR1 / NKP46

Background: Name/Gene ID: NCR1
Family: Immunoglobulin

Synonyms: NCR1, CD335, HNKp46, NK-p46, Lymphocyte antigen 94 homolog, NK cell-activating receptor, CD335 antigen, LY94, NKP46

Gene ID: 9437

UniProt: O76036

Pathways: Regulation of Leukocyte Mediated Immunity