RIPK3 antibody (AA 473-486)

Catalog No. ABIN1819402

This Rabbit Polyclonal antibody specifically detects RIPK3 in WB, IHC and IHC (p). It exhibits reactivity toward Mouse and Rat.

Quick Overview for RIPK3 antibody (AA 473-486) (ABIN1819402)

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIPK3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-RIPK3 Antibody

Binding Specificity: AA 473-486

Specificity: Recognizes mouse serine-threonine kinase receptor-interacting protein 3 (RIP3). RIP3 is related to RIP and RIP2 but does not posses a death domain or CARD motif at its C-terminus. RIP3 activates NF-Kappa B and potently induces apoptosis. RIP3 is expressed in a range of tissues including the spleen, liver, testis, heart, brain and lung.

Purification: Affinity purified

Immunogen: Synthetic peptide sequence corresponding to amino acids 473-486 of mouse RIP3.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, IHC-P (5 μg/mL), WB (0.5 - 1 μg/mL)

Comment:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for RIPK3

Target: RIPK3 (Receptor-Interacting serine-threonine Kinase 3 (RIPK3))

Alternative Name: RIPK3 / RIP3

Background: Name/Gene ID: RIPK3
Subfamily: RIP
Family: Protein Kinase

Synonyms: RIPK3, Receptor interacting protein 3, RIP-like protein kinase 3, RIP3, RIP-3, Receptor-interacting protein 3

Gene ID: 11035

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades